eATP Hypothesis PDF Print E-mail
Written by Marc C. E. Wagner   
Monday, 01 August 2011 11:32

The Therapeutic Potential of Adenosine Triphosphate as an Immune Modulator in the Treatment of HIV/AIDS: A Combination Approach with HAART


ATPPurinergic signaling involves the interaction of purine nucleosides and/or nucleotides with specific cell surface receptors. 


This field of study originating in the early 1970’s has evolved into an exciting area of research. 

Activation of these receptors has shown to result in a myriad of changes within a cell, which ultimately evokes a change in cell function. Extracellular adenosine triphosphate (eATP) offers a unique strategy for the eradication of the HIV latently cells from chronically infected individuals. 

eATP applied together with highly active antiretroviral (HAART) therapies possesses the potential in achieving the eradication result. 


eATP modulates the immune system in a manner that will enhance the host’s own defense mechanisms in reaching this goal. 


This complex hypothesis appears in the journal Current HIV Research and is available free of charge by visiting the website


The activation in the HIV reservoir followed by recognition and subsequent removal is the goal in the clinical application of ATP.


Key words: ATP, HIV reservoir, eATP
Last Updated on Monday, 01 August 2011 11:41

Dr. Dan Peterson 01.08.2012 (19:12:27)  
More info on some of what we discussed at last office visit Yes No  

Wondering if there are clinical trials like this for people like me on long term medication and declining quality of life problems.



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